KMID : 0361020210640100760
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Korean Journal of Otolaryngology - Head and Neck Surgery 2021 Volume.64 No. 10 p.760 ~ p.765
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Anaplastic Lymphoma Kinase Positive Large B-cell Lymphoma Mimicking Metastatic Carcinoma of the Cervical Lymph Node from an Unknown Primary Lesion
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Kim Sang-Woo
Lee Kyu-Ho Kim Bo-Hae Kim Eo-Jin
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Abstract
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Anaplastic lymphoma kinase positive large B-cell lymphoma (ALK+LBCL) is a rare subtypeof B-cell lymphoma with aggressive features and a poor prognosis. The rarity of this diseaseand similarity of microscopic features with undifferentiated epithelial neoplasm disturb theprovision of proper treatment. A 57-year-old male presented with a rapidly growing and painlessmass on the left side of the neck. Metastatic carcinoma of an unknown primary (CUP) lesionwas initially suspected based on the pathologic results obtained from a core needle biopsy,but it was finally diagnosed as ALK+LBCL after a modified radical neck dissection. We hereinreport a case of ALK+LBCL mimicking CUP with a literature review.
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KEYWORD
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Anaplastic lymphoma kinase, B-cell lymphoma, Unknown primary neoplasm
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